DIAGNOSTIC TECHNIQUE FOR ENDOGENOUS INTOXICATION Russian patent published in 2012 - IPC G01N33/48 G01N1/30 

FIELD: medicine.

SUBSTANCE: histological sections of internal organs are examined under a microscope; the histological examination is preceded by preparing a solution of diazotised aniline colour for staining the histological sections to detect indole, phenol, skatole; the histological section is stained and microphotographed; digital microphotos of the histological sections are processed on a computer. An average degree of staining with the diazotised aniline colour is estimated by the RGB colour grade system, and if observing the degree of staining within 250 to 100 RGB colour grade units, a mild severity of endogenous intoxication is diagnosed; the degree of staining varying from 100 to 50 RGB colour grade units shows a moderate severity of endogenous intoxication, while severe endogenous intoxication is indicated by the degree of staining being 50 to 0 RGB colour grade units.

EFFECT: using the technique enables higher toxicity and specificity of post-mortem diagnosis of endogenous intoxication based on the immediate detection of toxic metabolites collected in the internal organs.

1 tbl