FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to otorhinolaryngology, and concerns treating purulent rhinosinusitis. The method involves genetic typing by allelic polymorphism of interleukin-1 cytokine gene signs. The therapy is conducted if observing low-producing allele homozygous gene IL-1RA "1/1" in a patient. Following irrigation of the paranasal sinuses with isotonic solution is the introduction of the preparation of recombinant IL - 1RA in dosage 1.0 mg dissolved in 1.0-1.5 ml of isotonic solution in the paranasal sinuses. The introduction is conducted daily until purulence disappears.
EFFECT: method improves efficacy of the cytokine therapy of the patients with purulent rhinosinusitis by reducing length of treatment.
3 ex
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