NEW APPLICATION OF THERAPEUTICALLY EFFECTIVE PEPTIDES Russian patent published in 2012 - IPC A61K38/06 A61P9/00 A23C9/123 A23L1/305 

Abstract RU 2457852 C2

FIELD: medicine.

SUBSTANCE: tripeptides Ile-Pro-Pro (IPP) and/or Val-Pro-Pro (VPP) are applicable for preparing a product removing arterial stiffness and for preparing a product improving vascular elasticity. They are made of casein or casein-containing starting material by fermentation with the strain Lactobacillus helveticus DSM 13137 or Lactobacillus helveticus DSM 17754 and recovery by concentration and nanofiltration. The product contains a ferment composition containing the casein-recovered peptides Ile-Pro-Pro and/or Val-Pro-Pro, and living lactic acid bacteria. For the purpose of removing arterial stiffness, the product containing Ile-Pro-Pro and/or Val-Pro-Pro is introduced into an individual. For the purpose of improving vascular elasticity, the product containing Ile-Pro-Pro and/or Val-Pro-Pro is introduced into an individual with using said biologically active peptides.

EFFECT: invention promotes prevention and normalisation of endothelial dysfunction, improves vascular elasticity and removes arterial stiffness.

12 cl, 3 tbl, 5 ex

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RU 2 457 852 C2

Authors

Jaukhiajnen Tiina

Korpela Riitta

Vapaatalo Khejkki

Rennbak Mats

Dates

2012-08-10Published

2006-05-15Filed