FIELD: medicine, pharmaceutics.
SUBSTANCE: there are described new N-oxycarbonyl-substituted 5'-deoxy-5-fluorocytidines of general formula I wherein R1 represents a saturated normal or branched hydrocarbon radical wherein a number of carbon atoms in the longest direct chain makes three to seven, or a redical of formula -(CH2)n-Y, wherein n = 0 - 4; provided Y represents cyclohexyl, or n = 2 - 4, provided Y represents phenyl; R2 represents a hydrogen atom. What is described is an anti-cancer preparation based on the compounds of formula T.
EFFECT: compounds show the excellent high-safety pharmacokinetic properties in treating tumours.
6 cl, 7 tbl
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Authors
Dates
2012-08-20—Published
1993-12-16—Filed