FIELD: chemistry.
SUBSTANCE: invention relates to (1-benzylpiperidin-4-yl)-(4-alkoxypyridazin-3-y1)-amines of formula 
(I), in which radicals and symbols assume values given in the claim. Compounds of formula (I) are fast dissociating dopamine 2 receptor antagonists. The invention also relates to a pharmaceutical composition containing these compounds as an active ingredient.
EFFECT: compounds can be used as medicines for treating and preventing central nervous system disorders, for example schizophrenia, by exerting an antipsychotic effect without motor side effects.
9 cl, 4 ex
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| PYRIDINE DERIVATIVES USED AS QUICKLY DISSOCIABLE DOPAMINE RECEPTOR 2 ANTAGONISTS | 2008 |
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| 6,7-DIHYDROPYRAZOLO[1,5-A]PYRAZINE-4(5H)-ONE COMPOUNDS AND USE THEREOF AS NEGATIVE ALLOSTERIC MODULATORS OF mGluR2 RECEPTORS | 2015 |
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| IMIDAZOLE DERIVATIVES ACTIVE TO CB1 RECEPTOR | 2005 |
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| 6,7-DIHYDROPYRAZOLO[1,5-α]PYRAZIN-4(5H)-ONE COMPOUNDS AND USE THEREOF AS NEGATIVE ALLOSTERIC MODULATORS OF mGluR2 RECEPTORS | 2015 |
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RU2696135C2 |
| 6,7-DIHYDROPYRAZOLO[1,5-A]PYRAZINE-4(5H)-ONE COMPOUNDS AND USE THEREOF AS NEGATIVE ALLOSTERIC MODULATORS OF mGluR2 RECEPTORS | 2015 |
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| SUBSTITUTED 6-(1-PIPERAZINYL)-PYRIDAZINES AS 5-HT6 RECEPTOR ANTAGONISTS | 2009 |
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| ORGANIC COMPOUNDS | 2014 |
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RU2679142C2 |
| COMPOUNDS | 2003 |
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RU2327690C2 |
