FIELD: medicine; pharmaceuticals.
SUBSTANCE: invention relates to novel derivatives of 6,7-dihydropyrazolo[1,5-a]pyrazine-4(5H)-one of formula (I), as well as to pharmaceutical compositions containing such compounds.
(I).
EFFECT: technical result: novel compounds which can be used in the form of negative allosteric modulators (NAM) of metabotropic glutamate receptors of subtype 2 (mGluR2) and can be suitable for preventing or treating disorders in which subtype mGluR2 participates.
10 cl, 8 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| 6,7-DIHYDROPYRAZOLO[1,5-α]PYRAZIN-4(5H)-ONE COMPOUNDS AND USE THEREOF AS NEGATIVE ALLOSTERIC MODULATORS OF mGluR2 RECEPTORS | 2015 |
|
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| 6,7-DIHYDROPYRAZOLO[1,5-A]PYRAZINE-4(5H)-ONE COMPOUNDS AND USE THEREOF AS NEGATIVE ALLOSTERIC MODULATORS OF mGluR2 RECEPTORS | 2015 |
|
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|
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|
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| COMBINATIONS COMPRISING PDE 2 INHIBITORS SUCH AS 1-ARYL-4-METHYL- [1,2,4]TRIAZOLO[4,3-A]QUINOXALINE COMPOUNDS AND PDE 10 INHIBITORS FOR USE IN TREATMENT OF NEUROLOGICAL OR METABOLIC DISORDERS | 2013 |
|
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|
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