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2 466 132

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IPC

C07D487/22(2006-01-01)

A61K31/00(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2011108627/04, 2011-03-09

(24)

Start date

2011-03-09

(22)

Actual filing date

2011-03-09

(45)

Published

2012-11-10

(72)

Inventor

Danilenko Valerij NikolaevichLakatosh Sergej AleksandrovichPreobrazhenskaja Marija NikolaevnaShtil' Aleksandr Al'Bertovich

(73)

Holder

Avtonomnaja Nekommercheskaja Organizatsija Tsentr Biotekhnologii Antibiotikov I Drugikh Biologicheskikh Aktivnykh Veshchestv

PIM1-KINASE INHIBITOR 6-[(4-METHYL-I-1-PIPERAZINYL)METHYL]-INDOLO[1',7':1,2,3]PYRROLO[3',4':6,7]AZEPINO[4,5-b]INDOLE-1,3(2H, 10H)-DIONE, METHOD FOR PREPARING AND USING IT Russian patent published in 2012 - IPC C07D487/22 A61K31/00 A61P35/00

Abstract RU 2466132 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: what is described is the new compound 6-[(4-methyl-1-1-piperazinyl)methyl]-indolo[1',7':1,2,3]pyrrolo[3',4':6,7]azepino[4,5-6]indole-1,3(2H, 10H)-dione of formula , a method for preparing it and the use on the basis of observed activity as the Pim-1 proteinkinase inhibitor as an antitumour agent.

EFFECT: use of the Pim-1 proteinkinase inhibitor as an antitumour agent.

3 cl, 1 ex

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RU 2 466 132 C1

Authors

Danilenko Valerij Nikolaevich

Lakatosh Sergej Aleksandrovich

Preobrazhenskaja Marija Nikolaevna

Shtil' Aleksandr Al'Bertovich

Dates

2012-11-10—Published

2011-03-09—Filed