FIELD: medicine.
SUBSTANCE: invention refers to a method for prediction of cervical cancer in benign and pre-cancer cervical processes in females of reproductive age involving description of clinical risk factors of developing cervical cancer, MLH1, HIC1, RASSF1A, MGMT, N33, CDH1 gene methylation in a cervical biopsy material and calculation of a probability coefficient of developing cervical cancer p. If the value p is more than 0.6, a high probability of developing cervical cancer is predicted, the value p equal to 0.3-0.59 enables predicting a moderate probability of developing cervical cancer, and if the value p is less than 0.29, a low probability of developing cervical cancer is predicted.
EFFECT: method provides more accurate prediction of cervical cancer in benign and pre-cancer cervical diseases in females of reproductive age.
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Authors
Dates
2012-11-10—Published
2011-02-15—Filed