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2 405 837

(13)

(51)

IPC

C12Q1/68(2006-01-01)

(21) (22)

Application

2009125590/14, 2009-07-06

(24)

Start date

2009-07-06

(22)

Actual filing date

2009-07-06

(45)

Published

2010-12-10

(72)

Inventor

Kekeeva Tat'Jana VladimirovnaNemtsova Marina VjacheslavovnaShegaj Petr ViktorovichZaletaev Dmitrij Vladimirovich

(73)

Holder

Gosudarstvennoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Moskovskaja Meditsinskaja Akademija Im. I.M. Sechenova Federal'Nogo Agentstva Po Zdravookhraneniju I Sotsial'Nomu Razvitiju Mma Im. I.M. Sechenova Roszdrava)

EARLY DNA-DIAGNOSTIC TECHNIQUE OF PROSTATE CANCER Russian patent published in 2010 - IPC C12Q1/68

Abstract RU 2405837 C1

FIELD: medicine.

SUBSTANCE: blood serum is analysed for promoter region methylation of GSTP, p16 and N33 genes by methyl-sensitive PCR method. If observing abnormal methylation at least in two of said genes, the presence of a disease is concluded.

EFFECT: higher accuracy of early DNA-diagnosis of prostate cancer ensured by the use blood serum DNA to be analysed, technique exhibits higher specificity due to the correct gene specification in a test system and allows applying profit-proved detection methods.

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RU 2 405 837 C1

Authors

Kekeeva Tat'Jana Vladimirovna

Nemtsova Marina Vjacheslavovna

Shegaj Petr Viktorovich

Zaletaev Dmitrij Vladimirovich

Dates

2010-12-10—Published

2009-07-06—Filed