METHOD FOR ASSESSING OSTEOCYTE INVOLVEMENT IN BONE MATRIX MINERALISATION Russian patent published in 2012 - IPC G01N33/52 C12N5/16 

Abstract RU 2466408 C1

FIELD: medicine.

SUBSTANCE: osteons and intermediate lamellas are delineated and framed as members of analysis; osteocyte lacunae are numbered in each formed image; total number is presented, as well as a number of lacunae containing minerals in an amorphous phase. A percentage of the latter is described as a coefficient of osteocyte involvement in bone matrix mineralisation. If the minerals in the amorphous phase are found in less than 30% of lacunae, mineralisation activity of osteocyte is considered to be low. The presence of the amorphous minerals in 30-80% of lacunae shows moderate activity, and if more than 80% of lacunae contain the minerals in the amorphous phase, high activity is stated.

EFFECT: improved assessment accuracy.

1 ex, 2 dwg

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RU 2 466 408 C1

Authors

Shchudlo Mikhail Moiseevich

Dates

2012-11-10Published

2011-10-03Filed