METHOD FOR CONDUCTING INTRAORGANIC MEDICINE ELECTROPHORESIS OF BLADDER Russian patent published in 2012 - IPC A61N1/04 A61N1/30 A61K31/10 A61K31/407 A61P13/10 

FIELD: medicine.

SUBSTANCE: bladder is released, washed with distilled water, and a drug solution is introduced therein. An intrabladder electrode representing a catheter provided with a cylinder on its proximal end and three tips on its distal end, as well as with an electrical conductor with its distal end coupled with a current source. One of the tips is used to fill the cylinder with air or physiological saline, and another one - to introduce drug substances, and the electrical conductor is wired through the third tip. On a proximal end of the catheter, there are window openings for liquid injection and ejection from a bladder cavity. At a level of these openings, inside of the catheter, there is a steel guide presented in the form of a symmetrical single spiral wound with turns touching of the diametre matched with an internal diametre of the catheter, and of the length 1/3 exceeding the length of said openings. An external electrode is presented in one layer of pull-ups made of a combined cloth consisting of elastane, wool and metal in the relation of 1:16:16. The electrode is processed by a conducting gel used to coat pelvic and perineal regions.

EFFECT: improved drug penetration into bladder tissues, including in patients with decreased physiological volume of bladder ensured by more tight adherence of the external electrode to the pelvic and perineal regions and increased skin current conductivity, eliminated direct contact of the intrabladder electrode with a bladder mucosa, avoiding injuries of the bladder walls.

2 dwg, 2 ex