FIELD: chemistry.
SUBSTANCE: described is method of obtaining 7-membered heterocyclic compounds of formula 
(R-Ia) and 
(S-Ia), where values of radical are given in formula of the invention, basing on compound 
(Vaa) via corresponding isocyanate derivative and interaction of the latter with corresponding diazepin reagent.
EFFECT: target compounds possess inhibiting activity with respect to chymase.
2 cl, 331 ex, 12 tbl
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