FIELD: chemistry.
SUBSTANCE: described are novel 7-member heterocyclic compounds of general formula (values of radicals are given in the claim) or salts thereof or solvates thereof having chymase inhibiting activity and suitable for preventing or treating different diseases in which chymase is involved, a method of producing said compounds, intermediate compounds and a pharmaceutical composition for preventing or treating diseases in which chymase is involved, including compounds of formula (I) or pharmaceutically acceptable salts or solvates thereof.
EFFECT: improved properties of the compound.
23 cl, 12 tbl, 308 ex
Title | Year | Author | Number |
---|---|---|---|
7-MEMBERED CYCLIC COMPOUNDS, METHODS OF THEIR OBTAINING AND THEIR PHARMACEUTICAL APPLICATION | 2007 |
|
RU2466994C2 |
CONDENSED HETEROCYCLIC COMPOUND | 2009 |
|
RU2480473C2 |
DERIVATIVES OF ADAMANTANE, METHOD FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION AND METHOD FOR PREPARING PHARMACEUTICAL COMPOSITION | 1998 |
|
RU2214997C2 |
USING SIP RECEPTOR MODULATORS IN OPHTHALMOLOGY | 2006 |
|
RU2497513C2 |
PYRIDYLALKENE AND PYRIDYLALKYNE ACID AMIDES, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD OF ITS PREPARING | 1997 |
|
RU2200734C2 |
DERIVATIVES OF BENZAMIDE, METHOD OF THEIR PRODUCTION AND THEIR APPLICATION, PHARMACEUTICAL COMPOSITION AND METHOD FOR PROVISION OF INHIBITING ACTION IN RESPECT TO HDAC | 2003 |
|
RU2376287C2 |
DERIVATIVES OF 4-(1-PIPERAZINYL)-BENZOIC ACID, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION | 1997 |
|
RU2178786C2 |
BENZOTHIADIAZEPINE DERIVATIVES AND METHOD FOR PRODUCTION THEREOF (VARIANTS) | 2002 |
|
RU2305681C2 |
α-(1-PIPERAZINYL)-ACETAMIDO-DERIVATIVES OF ARENE CARBOXYLIC ACID, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT | 1998 |
|
RU2198881C2 |
TRIAZOLOPYRIDAZINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | 2014 |
|
RU2677698C1 |
Authors
Dates
2012-04-20—Published
2005-12-01—Filed