METHOD OF STAUROSPORIN PURIFICATION AND METHOD OF OBTAINING N-BENZOYLSTAUROSPORIN Russian patent published in 2012 - IPC C07D491/22 

Abstract RU 2467012 C2

FIELD: chemistry.

SUBSTANCE: invention relates to method of staurosporin purification, which includes obtaining staurosporin solution in first solvent, where first solvent represents benzyl ancohol; introduction into solution of purified staurosporin seeding in second solvent; and separation of product. Also described is method of obtaining N-benzoylstaurosporin, including reaction of staurosporin with benzoic anhydride with formation of solution; introduction into solution of amorphous N-benzoylstaurosporin; and separation of product.

EFFECT: method improvement.

3 cl, 3 dwg, 1 tbl, 16 ex

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RU 2 467 012 C2

Authors

Ehn Paskal'

Kokh Bernd

Mutts Mikhaehl'

Dates

2012-11-20Published

2005-11-03Filed