FIELD: medicine, pharmaceutics.
SUBSTANCE: claimed is application of tapentadol for manufacturing medication for treatment of pain caused by osteoarthrosis, in which at the beginning of treatment amount of taken in tapentadol is gradually increased in order to avoid side effects (titration from 25 mg two times per day to 200 mg two times per day).
EFFECT: reduction of prevalence of treatment side effects: day drowsiness, nausea, vomiting, dizziness and dry mouth.
13 cl, 4 dwg, 4 ex
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