FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to the use of tapentadol for preparing a drug containing at least one intake unit A containing tapentadol dose a, and at least one intake unit B containing tapentadol dose b wherein dose a < dose b for pain management, to a kit for pain management and to a method of pain management.
EFFECT: what is shown is improved tapentadol tolerance, especially reduced sleepiness accompanying pain management, especially in chronic pain, with no efficacy reduction.
37 cl, 10 dwg
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