FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to the use of a live mycobacterium of the complex M. tuberculosis wherein a zmpl gene function is inactivated for making a drug, pharmaceutical compositions prepared of such mycobacteria, as well as a method for prevention and/or treatment of diseases or conditions involved in antigen and/or immunogen expression in the mycobacterium. The mycobacterium used according to the invention may contains a genetic material coding an antigen and/or immunogen exogenic or xenogenic for the mycobacterium.
EFFECT: invention provides the live mycobacterium based drug with improved immunogenicity and protection effectiveness.
12 cl, 4 dwg, 3 ex
