METHOD OF PRODUCING 5-HYDROPEROXY-3,5-DIMETHYL-1,2-DIOXOLAN-3-OL Russian patent published in 2013 - IPC C07D317/04 

FIELD: chemistry.

SUBSTANCE: present invention relates to chemistry of organic peroxides, ketone derivatives, and specifically to a method of producing 5-hydroperoxy-3,5-dimethyl-1,2-dioxolan-3-ol of formula (I):

,

by reacting acetyl acetone with hydrogen peroxide, which is characterised by that the process is carried out in the presence of an acid catalyst HClO₄ in the medium of an organic solvent CH₃CN in molar ratio acetyl acetone: hydrogen peroxide: HClO₄ of 1:2:0.02-0.04 at room temperature of (20-25°C) for 3-6 hours. This method enables to obtain only one peroxide from acetyl acetone, which, unlike mixtures of acetyl acetone peroxides, has predictable and reproducible properties as a polymerisation initiator, and can be used an individual substance in organic synthesis of structures with antiparasitic activity and can be used in polymer chemistry, medicine and pharmacology.

EFFECT: safety and technological effectiveness of the method while maintaining sufficiently high output of the end product (71-75%).

1 cl, 2 ex