FIELD: chemistry.
SUBSTANCE: invention relates to a method for synthesis of an (E)-stilbene derivative of formula (I)-(E) or a (Z)-stilbene derivative of formula (I)-(Z): where values of substitutes R, R4-R9 are as given in the claim, which exhibit a variety of therapeutic properties. The method involves removing the protection from the corresponding compound of formula (II)-(E) or (II)-(Z): where A is hydrogen or a group OR'1, and R1, R2, R3 and R'1 are as given in the claim, by using an aluminium halide and a tertiary amine of formula NRaRbRc, where Ra, Rb and Rc independently denote a linear or branched C1-C4-alkyl group.
EFFECT: invention enables to obtain the end products using an industrially adequate method.
17 cl, 6 ex
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Authors
Dates
2013-02-10—Published
2008-09-23—Filed