FIELD: biotechnology.
SUBSTANCE: method for production of a formula III compound or a salt thereof,
. The compound of formula 
or its salt is brought into contact with ketoreductase or alcohol dehydrogenase enzyme.
EFFECT: invention allows stereoselective reduction of a compound of formula II or a salt thereof to a compound of formula III or a salt thereof that is suitable for further synthesis of ACT protein kinase activity inhibitors.
15 cl, 3 dwg, 2 tbl, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PRODUCING PYRIMIDINYLCYCLOPENTANE COMPOUNDS | 2014 |
|
RU2702355C1 |
| METHOD OF PRODUCING PYRIMIDINYLCYCLOPENTANE COMPOUNDS | 2014 |
|
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| BIOMARKERS FOR PREDICTION OF SENSITIVITY TO ANTITUMOR TREATMENT | 2012 |
|
RU2635193C2 |
| FORMS AND COMPOSITION OF PYRIMIDINYL CYCLOPENTANE COMPOUNDS, COMPOSITIONS AND METHODS THEREOF | 2013 |
|
RU2650511C2 |
| HYDROXYLATED AND METHOXYLATED CYCLOPENTA[B]PYRIMIDINES AS PROTEIN KINASE INHIBITORS | 2007 |
|
RU2478632C2 |
| COMBINATIONS OF AKT INHIBITOR COMPOUNDS AND ABIRATERONE, AND APPLICATION METHODS | 2012 |
|
RU2631240C2 |
| CYCLOPENTA(D)PYRIMIDINES AS PROTEIN KINASE AKT INHIBITORS | 2007 |
|
RU2481336C2 |
| METHODS OF PRODUCING (CYCLOPENTYL[D]PYRIMIDIN-4-YL)PIPERAZINE COMPOUNDS | 2015 |
|
RU2712224C2 |
| METHODS OF PRODUCING (CYCLOPENTYL[D]PYRIMIDIN-4-YL)PIPERAZINE COMPOUNDS | 2015 |
|
RU2732404C2 |
| HYDROXYLATED PYRIMIDYL CYCLOPENTANE AS PROTEINKINASE (ACT) INHIBITOR | 2009 |
|
RU2520735C2 |
