METHOD TO PRODUCE WATER-SOLUBLE OLIGOMER HOMOLOGS OF CHITOSANS IN HETEROGENEOUS SYSTEM Russian patent published in 2013 - IPC C08B37/08 

Abstract RU 2479590 C1

FIELD: biotechnologies.

SUBSTANCE: method includes depolymerisation of a high-molecular chitosan with hydrogen peroxide. The process of chitosan depolymerisation is carried out in a double-phase system. The solid phase is activated chitosan with Mav = 450-650 kDa and the average particle size of 0.05-0.20 mm. The liquid phase is a water solution of H2O2 with concentration of H2O2 in a reaction system equal to 1-7%. The reaction is carried out for 120-180 minutes at 70°C. Then phase separation of produced chitosan homologs is carried out by means of filtration via paper or textile surface of the produced reaction mixture. The produced filtrate contains water-soluble chitosan oligomers.

EFFECT: invention makes it possible to quantitatively control extent of conversion of an initial high-molecular chitosam into oligomer and low-molecular structures of its homologs.

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RU 2 479 590 C1

Authors

Slivkin Aleksej Ivanovich

Lapenko Viktor Lavren'Evich

Slivkin Denis Alekseevich

Bykov Valerij Alekseevich

Bychuk Aleksandr Ivanovich

Dates

2013-04-20Published

2011-10-12Filed