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2 481 335

(13)

(51)

IPC

C07D233/50(2006-01-01)

A61K31/4168(2006-01-01)

A61P27/02(2006-01-01)

A61P29/00(2006-01-01)

(21) (22)

Application

2010108386/04, 2008-08-14

(24)

Start date

2008-08-14

(22)

Actual filing date

2008-08-14

(45)

Published

2013-05-10

(72)

Inventor

Sinkha Santosh S.Bkheht Smita S.Khejdel'Bau Tod M.Dzhil Dehniel V.Chou KenGarst Majkl E.

(73)

Holder

Allergan, Ink.

CONDENSED CARBOCYCLE SUBSTITUTED DIHYDROIMIDAZOLE DERIVATIVES USED FOR PAIN CONTROL OR MANAGEMENT OF GLAUCOMA-LIKE CONDITIONS Russian patent published in 2013 - IPC C07D233/50 A61K31/4168 A61P27/02 A61P29/00

Abstract RU 2481335 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to a method of intraocular pressure reduction and to a method of pain control involving the administration of a therapeutic compound representing , or its tautomer or stereoisomer forms wherein X represents NH; n is equal to 2 or 3; R^a, R^b, R^c and R^d represent stable functional groups independently consisting of: 0 to 4 carbon atoms, 1 to 9 hydrogen atoms; and R^e represents H or C_1-4alkyl. Furthermore, the invention refers to a compound represented by formula , or to its tautomer or stereoisomer form.

EFFECT: new compound is prepared; besides, the known compounds to be applied in pain and glaucoma control are studied.

8 cl, 1 tbl

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RU 2 481 335 C2

Authors

Sinkha Santosh S.

Bkheht Smita S.

Khejdel'Bau Tod M.

Dzhil Dehniel V.

Chou Ken

Garst Majkl E.

Dates

2013-05-10—Published

2008-08-14—Filed