HETEROCYCLIC INDANE DERIVATIVES USED TO CONTROL PAIN AND TREAT GLAUCOMOID STATE Russian patent published in 2013 - IPC C07D233/50 A61K31/4168 A61P27/06 A61P29/00 

Abstract RU 2491278 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to a method of controlling pain and reducing intraocular pressure involving the administration of a compound of formula , wherein X represents O, S or NH; Ra, Rb, Rc and Rd are independently specified in H, methyl, ethyl, C3 alkyl and C4 alkyl, F, Cl Br, -CH2OH, -CH2NH2, -CHNH(C1-4 alkyl), -CN(C1-4 alkyl)2, -CH2CN and CF3; and Re represents H or C1-4 alkyl. Also, the invention refers to specific indane derivatives.

EFFECT: there are presented new methods of using the known compounds, as well as there are produced new indane derivatives effective in controlling pain and reducing intraocular pressure.

16 cl, 1 tbl, 6 ex

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RU 2 491 278 C2

Authors

Chou Ken

Fang Vehnkuj K.

Korpuz Ehvelin G.

Gomez Dario G.

Sinkha Santosh S.

Bkheht Smita S.

Khejdel'Bau Tod M.

Dzhil Dehniel V.

Dates

2013-08-27Published

2008-08-14Filed