THERAPEUTIC SUBSTITUTED LACTAMS Russian patent published in 2013 - IPC C07D409/06 C07D409/12 A61K31/4025 A61P27/06

Abstract RU 2481342 C9

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a compound of formula: , wherein Y represents -CO₂H; A represents -(CH₂)_m-Ar-(CH₂)_o-, wherein Ar represents thiophenyl; total m and o is equal to 3, and wherein 1 group -CH₂- may be substituted by O; G and G' represents -H; and B represents phenyl containing 1 to 2 substitutes independently specified in -F, -Cl and -Br. The invention also refers to a composition on the basis of the mentioned compounds.

EFFECT: there are produced new compounds and pharmaceutical composition on their basis which can find application in medicine for treating glaucoma or ocular hypertension.

10 cl, 1 tbl, 2 ex

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RU 2 481 342 C9

Authors

Old Dehvid V.

Ngo Vinkh Ks.

Dates

2013-05-10—Published

2008-10-16—Filed