THERAPEUTIC COMPOUNDS Russian patent published in 2013 - IPC C07D295/88 C07D265/30 A61K31/5575 A61P1/04 A61P17/14 A61K31/22 A61P27/06 A61K31/5375 

FIELD: chemistry.

SUBSTANCE: invention relates to novel compounds having the structure or pharmaceutically acceptable salts thereof, where Y is or ; A is -(CH₂)₆-, cis-CH₂CH=CH-(CH₂)₃- or -CH₂C=C-(CH₂)₃-, where 1 or 2 carbon atoms can be substituted with S or O; or A is -(CH₂)_m-Ar-(CH₂)₀-, where Ar is interarylene or heterointerarylene, the sum of m and o is equal to 1, 2, 3 or 4, and where one CH₂ can be substituted with S or O; J is C=O, CHOH, CHF, CHCl, CHBr, CF₂, CCl₂, CBr₂ or CHCN; and B is aryl or heteroaryl, substituted with C_1-10 oxoalkyl. The invention also relates to a method of treating balding, which involves administering a therapeutically effective amount of said compound to a subject in need of such treatment.

EFFECT: high efficiency of using the compound.

11 cl