DIOXOANTHRACENE SULPHONATE DERIVATIVES Russian patent published in 2013 - IPC C07C309/38 C07C309/43 A61K31/10 A61K31/192 A61K31/185 A61P29/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a compound having formula (I): wherein each of the groups R₁, R₂, R₃ are independently H or C_1-4 alkyl group or C_2-4 acyl group; each of the groups R₄ and R₅ are independently H or the group of formula -SO₃R₆, wherein R₆ is H or the C_1-4 alkyl group or the C_2-4 acyl group; provided at least one of the groups R₄ and R₅ is a group having formula -SO₃R₆, or a pharmaceutically acceptable salt thereof. The invention also refers to a method for preparing the specified compounds of formula (I) and a pharmaceutical composition possessing activity in the inhibition of IL-1 anti-inflammatory cytokines based on these compounds.

EFFECT: there are produced new compounds and pharmaceutical composition on their basis which can find application in medicine for treating an inflammatory or autoimmune condition.

17 cl, 4 dwg, 4 ex