INHIBITORS OF NO-SYNTHASE BASED ON MERCAPTO- AND SELENODERIVATIVES Russian patent published in 2002 - IPC

FIELD: medicine, biochemistry, pharmacy. SUBSTANCE: invention relates to pharmacologically acceptable composition for inhibition of activity of NO-synthase in mammal that comprises mercapto- or selenoderivative and pharmaceutically acceptable carrier. Invention relates to also method of inhibition of activity of NO-synthase, in part, method that inhibits activity of inducible isoform of NO-synthase selectively. Invention relates to also treatment of different states where inhibition of biosynthesis of nitrogen oxide is expediently by administration in mammal of mercapto- or selenoderivative in pure form or in pharmaceutically acceptable carrier. EFFECT: enhanced effectiveness of treatment. 45 cl, 10 dwg, 6 tbl