FIELD: medicine.
SUBSTANCE: invention refers to treatment and/or prevention of the disease of the object in need thereof, wherein the disease is selected from a group comprising uveitis and epidermolytic ichthyosis (EI). For this purpose, the treatment and/or prevention of the disease involves administering to the said object a therapeutically effective amount of a compound selected from a group, consisting of diacerein, rhein, monoacetyl rhein and therapeutically acceptable salts and esters.
EFFECT: invention provides suppressing the expression of ASC and NLRP3, thereby inhibiting formation of an assembly of ASC-spots and the NLRP3 complex inflammasomes.
3 cl, 1 ex, 3 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| METHODS AND COMPOSITIONS FOR TREATING HYPERURICEMIA AND METABOLIC DISORDERS ASSOCIATED WITH HYPERURICEMIA | 2012 |
|
RU2603050C2 |
| DIOXOANTHRACENE SULPHONATE DERIVATIVES | 2008 |
|
RU2482109C2 |
| USE OF MELATONIN FOR TREATING AND/OR PREVENTING MUCOSITIS | 2012 |
|
RU2600446C2 |
| MEDICINES CONTAINING DIACEREIN, AND METHODS FOR REDUCING URIC ACID LEVELS IN BLOOD WITH USING THEREOF | 2015 |
|
RU2690372C2 |
| PHARMACEUTICAL COMPOSITIONS CONTAINING DIACEREIN | 2009 |
|
RU2542461C2 |
| METHODS OF DIACEREIN APPLICATION IN ADDITIONAL TREATMENT OF DIABETES | 2011 |
|
RU2563988C2 |
| SUBSTANCES USABLE FOR TREATING PSORIASIS CASES | 2001 |
|
RU2266740C2 |
| CCR5 EXPRESSION SUPRESSION COMPOSITIONS AND METHODS OF APPLICATION THEREOF | 2004 |
|
RU2353357C2 |
| METHOD FOR INCREASING THE EXPRESSION OF ENCODED RNA PROTEINS | 2014 |
|
RU2733424C2 |
| INTEGRIN ανβ8 NEUTRALISING ANTIBODIES | 2011 |
|
RU2565539C2 |
