NEW 4-(HETEROCYCLOALKYL)BENZENE-1,3-DIOL COMPOUNDS AS TYROSINE KINASE INHIBITORS, METHOD FOR PREPARING THEM AND USING THEM IN TREATING INDIVIDUALS, AS WELL AS IN COSMETIC PRODUCTS Russian patent published in 2013 - IPC C07D307/12 C07D307/04 C07D309/06 C07D333/16 A61K31/341 A61K31/351 A61K31/381 A61K31/382 A61P17/00 A61Q19/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to new 4-(heterocycloalkyl)benzene-1,3-diol compounds described by general formula (I) presented below, wherein: R1, R2, R3 and R4 may be identical or different, and represent: - hydrogen,- C₁-C₄-alkyl radical,- hydroxymethyl, hydroxyethyl, - (C₁-C₄-alkoxy) carbonyl,- C₁-C₄-alkoxy,- hydroxyl, or R1 and R2 are bound to each other and to a carbon atom whereto attached to form a carbon cycle containing 5 or 6 carbon atoms, while R3 and R4 may be identical or different, and represent: - hydrogen, - C₁-C₄-alkyl radical, or R1 and R4 are bound to each other to form the chain -(CH₂)₂- or -(CH₂)₃-, while R2 and R3 may be identical or different, and represent: - hydrogen, - C₁-C₄-alkyl radical, X represents an oxygen atom or a sulphur atom, Y represents hydrogen, a chlorine atom or a fluorine atom, the value of m may represent 1 or 2, while the value of n may represent 0 or 1, and provided n=0, then m=1 or 2, and provided n=1, then m=1, as well as to salts of the compounds of general formula (I) and to their isomer and enantiomer forms.

EFFECT: invention relates to the use of these compounds in pharmaceutical or cosmetic compositions for the use in treating or preventing pigmentary disorders.

7 cl, 2 tbl, 19 ex