TREATMENT AND PREVENTION OF NEURODGENERATIVE DISEASES WITH USE OF GENE THERAPY Russian patent published in 2013 - IPC A61K31/7115 A61P5/28 

Abstract RU 2471487 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely neurology, and concerns treatment and prevention of neurodegenerative diseases, particularly Alzheimer's disease with the use of gene therapy. That is ensured by the introduction of a composition containing one or more nucleic acids inducing cell immune response. The nucleic acids to be introduced code one or more cytokines specified in a group consisting of IL-4 (interleukine-4), IL-10 (interleukine-10) and TGF-β (transforming growth factor beta).

EFFECT: method provides reduced cerebral accumulations of amyloid formations.

16 cl, 7 ex, 7 dwg

Similar patents RU2471487C2

Title Year Author Number
MODIFIED MONOCYTES/MACROPHAGES EXPRESSING CHIMERIC ANTIGEN RECEPTORS AND THEIR APPLICATIONS 2016
  • Gill, Saar
  • Klichinsky, Michael
  • June, Carl H.
RU2766690C2
VECTORS CONDITIONALLY EXPRESSING THERAPEUTIC PROTEINS, HOST CELLS COMPRISING THE VECTORS, AND USES THEREOF 2011
RU2612788C2
NUCLEIC ACID SYNTHETIC MOLECULE (VERSIONS), MAMMAL CELL EXPRESSION VECTOR, MAMMAL HOST CELL AND METHOD OF EXPRESSING ANTIGEN PROTEIN OF HUMAN EPIDERMAL GROWTH FACTOR-2 (HER2/neu) OR SHORTENED FORM THEREOF 2004
  • Gallo Paskual'
  • Monachi Paolo
  • Nutstso Mauritsio
RU2397249C2
FUSED PROTEIN OF TELOMERASE REVERSE TRANSCRIPTASE, NUCLEOTIDES CODING THEM, AND USING THEM 2007
  • Chiliberto Dzhennaro
  • La Monika Nikola
  • Mennuni Karmela
  • Skarselli Ehliza
RU2473691C2
ANTI-HCV VACCINE 2003
  • Brett Sara
  • Khehmblin Pol Ehndrju
  • Ogilvi Luiz
RU2323744C2
MODIFIED DENDRITE CELLS AND THEIR USE IN TREATMENT OF MALIGNANT TUMOURS 2008
  • Brauler Dzh. Mark
  • Kumar Prasanna
  • Storkus Uolter Dzh.
  • Okada Khidekho
RU2484132C2
CONSTRUCTED CELLS, EXPRESSING MULTIPLE IMMUNOMODULATORS, AND THEREOF APPLICATION 2009
  • Bich Robert Patterson
  • Rid Tomas D.
RU2573912C2
MODIFIED DENDRITIC CELLS AND THEIR APPLICATION FOR MALIGNANT TUMOURS TREATMENT 2013
  • Brauler Dzh. Mark
  • Kumar Prasanna
  • Storkus Uolter Dzh.
  • Okada Khidekho
RU2644210C2
LIGAND GITR AND MOLECULES AND ANTIBODIES BOUND WITH LIGAND GITR, AND VERSIONS OF THEIR APPLICATION 2004
  • Kollinz Mehri
  • Shevach Ehtan Menakhem
  • Makkh'Ju Rebekka S'Juzn
  • Uitters Mehtt'Ju Dzhejms
  • Jang Debora Ehnn
  • Birn Majkl Chehpmen
  • Reddi Padmalata F.
  • Stefenz Dzhoffri Lorens
  • Karreno Beatriz M.
RU2369636C2
FUSED PROTEINS OF CARCINOEMBRYONAL ANTIGEN 2005
  • La Monika Nikola
  • Fachch'Jabene Andrea
  • Aurisichch'O Luidzhi
  • Chiliberto Dzhennaro
RU2380375C2

RU 2 471 487 C2

Authors

Joo Taj Dzhun

Dates

2013-01-10Published

2008-02-04Filed