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(11)

2 486 190

(13)

(51)

IPC

C07D487/08(2006-01-01)

C07D513/08(2006-01-01)

A61K31/407(2006-01-01)

A61P31/12(2006-01-01)

(21) (22)

Application

2010130984/04, 2008-12-23

(24)

Start date

2008-12-23

(22)

Actual filing date

2008-12-23

(45)

Published

2013-06-27

(72)

Inventor

Rabuasson P'Er Zhan-Mari BernarKhu LiliVendevill' SandrinNiangil' OrizhenTakhri Abdellakh

(73)

Holder

Tibotek Farmas'Jutikalz

MACROCYCLIC INDOLES AS HEPATITIS C VIRUS INHIBITORS Russian patent published in 2013 - IPC C07D487/08 C07D513/08 A61K31/407 A61P31/12

Abstract RU 2486190 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to new compounds of formula I:

or pharmaceutically acceptable salts thereof, wherein the values R¹, R³, and R⁴are specified in cl. one of the patent claim.

EFFECT: compounds inhibit the HCV replication that makes them applicable for preparing a pharmaceutical composition and a drug preparation for HCV infection.

16 cl, 3 tbl, 10 dwg, 30 ex

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RU 2 486 190 C2

Authors

Rabuasson P'Er Zhan-Mari Bernar

Khu Lili

Vendevill' Sandrin

Niangil' Orizhen

Takhri Abdellakh

Dates

2013-06-27—Published

2008-12-23—Filed