AZACYTIDINE ANALOGUES AND USE THEREOF Russian patent published in 2013 - IPC C07H19/06 A61K31/7052 A61P35/00 A61P29/00 

Abstract RU 2487883 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a novel azacytidine analogue of formula (I): where R is H, R5C(O); R1 is or where the crossing dashed line denotes the formed bond joining R1 to a molecule of formula (I); R2 and R3 are independently OH or H provided that R2 and R3 are not OH at the same time; R4 is H or R5C(O) provided that R and R4 are not H at the same time; and R5 is C3-C26 alkenyl, or a pharmaceutical salt thereof.

EFFECT: compounds have anti-cancer and anti-inflammatory activity.

15 cl, 6 tbl, 7 dwg, 15 ex

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RU 2 487 883 C2

Authors

Silverman L'Juis

Kholland Dzhejms

Dates

2013-07-20Published

2008-09-25Filed