FIELD: chemistry.
SUBSTANCE: invention relates to a novel azacytidine analogue of formula (I): where R is H, R5C(O); R1 is or where the crossing dashed line denotes the formed bond joining R1 to a molecule of formula (I); R2 and R3 are independently OH or H provided that R2 and R3 are not OH at the same time; R4 is H or R5C(O) provided that R and R4 are not H at the same time; and R5 is C3-C26 alkenyl, or a pharmaceutical salt thereof.
EFFECT: compounds have anti-cancer and anti-inflammatory activity.
15 cl, 6 tbl, 7 dwg, 15 ex
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Authors
Dates
2013-07-20—Published
2008-09-25—Filed