METHOD FOR PLATELET AUTOANTIBODY TEST Russian patent published in 2013 - IPC G01N33/48 G01N33/49 G01N33/53 

Abstract RU 2488114 C1

FIELD: medicine.

SUBSTANCE: method consists in determining a percentage of immunoglobulin G and M coated platelets using flow cytometry. For the purpose of the analysis, own patient's platelets and blood serum are examined; autoimmune process markers are immunoglobulin G and M antibodies. A platelet autosensitisation index is calculated as ratio of Anti-Human IgG/IgM-positive cells to CD41 fixing cells: the platelet autosensitisation index more than 2% without autoserum incubation and more than 5% after autoserum incubation is considered as the presence of the antiplatelet autoantibodies fixed on cells and/or circulating in blood plasma.

EFFECT: higher diagnostic accuracy of immune thrombocytopenia, specifying a therapeutic approach and controlling the effectiveness thereof.

3 tbl, 2 ex

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RU 2 488 114 C1

Authors

Butina Elena Vladimirovna

Zajtseva Galina Alekseevna

Isaeva Natal'Ja Vasil'Evna

Vaskina Elena Alekseevna

Dokshina Irina Anatol'Evna

Dates

2013-07-20Published

2012-01-10Filed