FIELD: medicine; hematology.
SUBSTANCE: invention refers to diagnostics of immune blood diseases, and concerns diagnostics of alloimmune thrombocytopenia of newborns. Analyzed material, in the form of the paternal thrombocytes, is incubated with the maternal blood plasma, stained with labeled monoclonal antibodies, cell-fixed antibodies are detected on a flow cytofluorometer. Then the maternal allosensitization index is determined as a percentage of IgG-positive cells of the number of cells fixing anti-CD41 antibodies. If observing a maternal allosensitization value of not less than 15%, newborn alloimmune thrombocytopenia is diagnosed.
EFFECT: invention provides diagnosing alloimmune thrombocytopenia in newborns without using its blood.
1 cl, 2 tbl, 2 ex
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|---|---|---|---|
| METHOD FOR THE DIAGNOSIS OF ALLOIMMUNE THROMBOCYTOPENIA OF THE NEWBORN | 2015 |
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