METHOD OF PRODUCING NON-RACEMIC 1- (ADAMANT-1-YL) -2- (2-NITRO-1-PLENYLETHYL) BUTANE-1,3-DIONE Russian patent published in 2017 - IPC C07C201/12 C07C205/45 

Abstract RU 2612966 C1

FIELD: chemistry.

SUBSTANCE: invention relates to method of producing non-racemic 1- (adamant-1-yl) -2- (2-nitro-1-phenylethyl) butane-1,3-dione of formula I . The method is carried out by enantioselective joining of 1- (adamant-1-yl) butan-1,3-dione to ω-nitrostyrene in the presence of a nickel complex of formula II in accordance with the following scheme (R = H). The method is characterized by the fact that 1,3-diketone containing adamantyl substituent is used as the Michael donor.

EFFECT: invention enables to simplify the process, reduce its price and obtain the product with good output.

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Authors

Dates

2017-03-14Published

2015-12-04Filed