FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing (S)-pregabalin of formula I 
, which is used in therapy of a range of neuropathic diseases. The method includes enantioselective addition of diethyl malonate to 4-methyl-1-nitropentene-1 followed by reduction and acid hydrolysis of the addition product in accordance with the given scheme. The catalyst used at the addition step is a complex of nickel (II) of formula II 
with (S,S)-N,N'-dibenzylcyclohexane-1,2-diamine.
EFFECT: method reduces catalyst consumption, reduces the number of steps and amount of solvents used, thereby making the process simpler and cheaper.
4 cl, 10 ex
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