FIELD: biotechnologies.
SUBSTANCE: new strain "KEM-7" of the fowlpox virus is produced by multiple passages of mother virus on developing chicken embryos. The strain is deposited into the collection of FSBI VGNKI under the registration number (reference) - strain "KEM-7" - DEP of fowlpox virus. The strain is genetically authentic by the sequence of nucleotides of the gene 241ext. It is adapted to the organism of developing chicken embryos. It is immunogenic, moderately reactogenic and harmless for birds in case of an intradermal injection. It preserves the attenuated phenotype during passages both in the cultivation system and on a naturally receptive bird.
EFFECT: invention expands arsenal of vaccine strains of fowlpox virus, the strain is suitable for manufacturing of biopreparations of specific prevention and diagnostics of fowlpox virus.
6 cl, 3 dwg, 9 tbl, 8 ex
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