NANOEMULSION CONTAINING BIOLOGICALLY ACTIVE SUBSTANCE Russian patent published in 2013 - IPC A61K9/107 A61K36/00 A61K38/08 A61K47/26 A61K47/30 B82B1/00 B82Y5/00 

Abstract RU 2494728 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a nanoemulsion as a carrier of a biologically active substance representing a DSIP or a herbal extract. The nanoemulsion contains water, a surfactant representing an ethylene oxide/ propylene oxide block copolymer, and a biopolymer in the form of mixed polysaccharide (PS) and polyaminosaccharide (PAS). The polysaccharide is 2-diethylaminoethyl-dextran or 3-dimethylaminopropyl-dextran. The polyaminosaccharide is chitosan or a chitosan derivative prepared by exhaustive alkylation of primary amino groups by glycidyl trimethylammonium chloride. The mass content of each of the polymers (ethylene oxide/ propylene oxide block copolymer, PS and PAS) in the mixture of polymers and nanoemulsion is found within the range of 0.1 to 0.7, while the ethylene oxide/ propylene oxide block copolymer concentration makes 0.4-4.0 g/l.

EFFECT: invention provides preparing the biologically compatible and storage-stable nanoemulsion.

2 cl, 7 ex

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RU 2 494 728 C1

Authors

Prudchenko Igor' Arkad'Evich

Markvicheva Elena Arnol'Dovna

Filatova Ljubov' Jur'Evna

Kljachko Natal'Ja L'Vovna

Fel'Dman Boris Mordkovich

Dates

2013-10-10Published

2012-08-16Filed