CONJUGATE OF FOLIC ACID AND METHOD OF ITS OBTAINING Russian patent published in 2013 - IPC C07F5/00 A61K49/00 

Abstract RU 2497825 C1

FIELD: chemistry.

SUBSTANCE: invention relates to conjugate of folic acid. Conjugate includes folic acid and lanthanide chelate, bound via spacer L-alanine, bound to phenanthroline, and has general formula: . Where Ln represents ion Eu3+, Tb3+, Sm3+, Dy3+, Yb3+, Nd3+, Er3+, Tm3+. Also claimed is method of conjugate obtaining.

EFFECT: invention makes it possible to obtain conjugate, which is able to save spectral-luminescent properties in bio-objects and act as chemically and spectrally stable molecular probe.

2 cl, 2 dwg

Similar patents RU2497825C1

Title Year Author Number
DIFFERENT-LIGAND FLUORO-SUBSTITUTED AROMATIC LANTANIDE CARBOXYLATES, LUMINESCENT PROPERTIES, AND ORGANIC LED BASED DIODES 2017
  • Stefan Brase
  • Vashchenko Andrej Aleksandrovich
  • Kalyakina Alena Sergeevna
  • Solodukhin Nikolaj Nikolaevich
  • Aslandukov Andrej Nikolaevich
  • Shtefan Breze
  • Kuzmina Nataliya Petrovna
RU2657496C1
LANTHANIDE COMPLEXES EXHIBITING LUMINESCENT PROPERTIES, METHOD OF DETERMINING GLUCOSE CONCENTRATION BASED ON THEM 2022
  • Utochnikova Valentina Vladimirovna
  • Koshelev Daniil Sergeevich
  • Tselykh Lyubov Olegovna
  • Serbinov Oleg Anatolevich
RU2813337C1
TRIS-DIKETONATE COMPLEXES OF LANTHANIDES WITH PYRIDINE LIGANDS AS LUMINOPHORES AND METHOD OF PRODUCING SAID COMPLEXES 2011
  • Fomina Marina Viktorovna
  • Vannikov Anatolij Veniaminovich
  • Lypenko Dmitrij Aleksandrovich
  • Mal'Tsev Evgenij Ivanovich
  • Pozin Sergej Igorevich
  • Dmitriev Artem Vladimirovich
  • Alfimov Mikhail Vladimirovich
  • Gromov Sergej Pantelejmonovich
RU2463304C1
CONJUGATES OF THERAPEUTIC COMPOUND WITH FATTY ACID 1996
  • Robert Dzhordzh Uittehjker
  • Veronika Dzhudit Bender
  • Uehjn Gerrard Rejlli
  • Minoo Mogkhaddam
RU2166512C2
CONJUGATES, CONTAINING HYDROPHILIC SPACERS OF LINKERS 2008
  • Limon Kristofer Pol
  • Van Juj
  • Vlakhov Iontcho Radoslavov
  • Ju Fehj
  • Klejndl Pol Dzhozef
  • Santkhapuram Khari Krishna R
RU2523909C2
POLYMERIC COMPLEX FOR MOLECULAR TARGETING THERAPY AND METHOD FOR ITS OBTAINING 2017
  • Poltavets Yurij Igorevich
  • Vorontsov Evgenij Alekseevich
  • Zavarzina Vasilisa Vitalevna
  • Gukasova Nadezhda Vadimovna
  • Kuznetsov Sergej Leonidovich
  • Tubasheva Irina Anatolevna
  • Aleshin Sergej Valerevich
  • Krasheninnikova Anna Andreevna
  • Dronov Danil Olegovich
  • Posypanova Galina Aronovna
  • Muraveva Anna Ivanovna
RU2675810C1
METHOD FOR TREATING CANCER BY TARGETING SUPPRESSOR CELLS OF MYELOID ORIGIN 2017
  • Lou, Filip Styuart
  • Van, Binbin
  • Limon, Kristofer Pol
  • Lu, Intszyuan Ts.
  • Uiler Ii, Leroj U.
RU2776899C2
PROTEIN-BINDING METHOTREXATE DERIVATIVES AND MEDICINES CONTAINING SAID DERIVATIVES 2007
  • Krats Feliks
  • Varneke Andre
RU2439077C2
CONJUGATE CONTAINING FOLIC ACID AND INDOLE-3-CARBINOL FOR MEDICAL USE 2014
  • Terenzio Domenico
  • Rastrelli Luca
RU2692078C2
RADIOACTIVE IMMUNOREAGENT OF THE DIRECTED EFFECT, A COMPOSITION FOR OBTAINING AN IMAGE OF MALIGNANT NEOPLASM IN BODY, A METHOD OF OBTAINING AN IMAGE AND A CHELATING AGENT 1992
  • Dzhon L.Touner
  • Dehvid A.Khilborn
  • Brjus Dzh.Mjurrej
  • Timoti Z.Khaussejn
  • Robert A.Snou
  • Asis K.Sakha
  • Richard Filion
  • Klajd V.Shirman
  • Chandra Shakh
RU2122431C1

RU 2 497 825 C1

Authors

Pavich Tat'Jana Aleksandrovna

Vorobej Aleksandr Vasil'Evich

Solov'Ev Konstantin Nikolaevich

Arabej Sergej Mikhajlovich

Dates

2013-11-10Published

2012-07-03Filed