EARLY DIAGNOSTIC TECHNIQUE FOR DEVELOPING PELVIC PROLAPSE IN FEMALES OF REPRODUCTIVE AGE WITH NO CLINICAL SIGNS Russian patent published in 2013 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: invention described an early diagnostic technique for the developing pelvic prolapse in the females of reproductive age with no clinical signs, consisting in sampling the vaginal wall tissue, conducting the histochemical analysis, determining the quantity and state of elastin fibrils, the content of matrix proteins LOXL1 and FBLN5, wherein the developing pelvic prolapse is diagnosed if observing the reduction in elastin fibrils and a fragmentation thereof in a combination with the reduction in matrix protein LOXL1 and FBLN5 in the epithelium, vascular endothelium, fibroblast, extracellular matrix as related to the same in the healthy females.

EFFECT: method enables assessing the pathophysiological processes observed at the initial preclinical signs of the developing pelvic prolapse that will enable the more accurate interpretation of the causes of the developing pelvic floor dysfunction, and also the working-out of the basic principles to prevent the development of the given pathology in the females of reproductive age.

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