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2 542 441

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IPC

G01N33/68(2006-01-01)

(21) (22)

Application

2013143349/15, 2013-09-25

(24)

Start date

2013-09-25

(22)

Actual filing date

2013-09-25

(45)

Published

2015-02-20

(72)

Inventor

Kamoeva Svetlana ViktorovnaMakarov Oleg Vasil'EvichKhadzhieva Mar'Jam BorisovnaIvanova Anastasija VladimirovnaChumachenko Anastasija Gennad'EvnaAbilev Serikbaj KarimovichSal'Nikova Ljubov' Efimovna

(73)

Holder

Gosudarstvennoe Bjudzhetnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Natsional'Nyj Issledovatel'Skij Meditsinskij Universitet Im. N.I. Pirogova Ministerstva Zdravookhranenija Rossijskoj Federatsii" Vpo Rnimu Minzdrava Rossii)

METHOD FOR PREDICTION OF RISK OF DEVELOPING GENITAL PROLAPSE IN FEMALES Russian patent published in 2015 - IPC G01N33/68

Abstract RU 2542441 C1

FIELD: medicine.

SUBSTANCE: biomaterial is sampled for DNA recovery. That is followed by the DNA genetic typing by tetra-primer allele-specific polymerase chain reaction. The polymorphism of FBLN5 gene in rs12586948 and rs2018736 sites are detected. A high risk of developing genital prolapse is predicted if observing the alleles of nucleotide variants of rs12586948-A and/or rs2018736-C. A lower risk is shown by the alleles of oligonucleotide variants of rs12586948-G and/or rs2018736-A.

EFFECT: invention enables detecting the patients with the high risk of developing genital prolapsed for the purpose of taking timely and aimed actions for preventing the given pathology.

1 dwg, 3 tbl, 3 ex

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RU 2 542 441 C1

Authors

Kamoeva Svetlana Viktorovna

Makarov Oleg Vasil'Evich

Khadzhieva Mar'Jam Borisovna

Ivanova Anastasija Vladimirovna

Chumachenko Anastasija Gennad'Evna

Abilev Serikbaj Karimovich

Sal'Nikova Ljubov' Efimovna

Dates

2015-02-20—Published

2013-09-25—Filed