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2 560 842

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IPC

G01N33/50(2006-01-01)

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Application

2014117256/15, 2014-04-29

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Start date

2014-04-29

(22)

Actual filing date

2014-04-29

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Published

2015-08-20

(72)

Inventor

Kamoeva Svetlana ViktorovnaMakarov Oleg Vasil'EvichKhadzhieva Mar'Jam BorisovnaIvanova Anastasija VladimirovnaChumachenko Anastasija Gennad'EvnaAbilev Serikbaj KarimovichSal'Nikova Ljubov' Efimovna

(73)

Holder

Gosudarstvennoe Bjudzhetnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Natsional'Nyj Issledovatel'Skij Meditsinskij Universitet Im. N.I. Pirogova Ministerstva Zdravookhranenija Rossijskoj Federatsii" Vpo Rnimu Minzdrava Rossii)

METHOD FOR PREDICTION OF RISK OF GENITAL PROLAPSE IN FEMALES HAVING CHILDBIRTH-RELATED INJURIES IN PAST MEDICAL HISTORY Russian patent published in 2015 - IPC G01N33/50

Abstract RU 2560842 C1

FIELD: medicine.

SUBSTANCE: invention represents a method for the prediction of a risk of genital prolapse (GP) in the females having childbirth-related injuries in the past medical history, involving sampling a biological material for DNA recovery, genotyping DNA by the tetra-primer allele-specific polymerase chain reaction, identifying FBLN5 gene polymorphism in rs12586948, rs2018736, rs12589592 and rs2474028 sites, and predicting the high risk of genital prolapse if stating a combination of: rs12586948-A/*, rs2018736-C/*, rs12589592-G/G and rs2474028-T/* genotypes, whereas the low risk is shown by a combination of: rs12586948-G/G, rs2018736-A/A, rs12589592-A/A and rs2474028-C/C genotypes.

EFFECT: extending the range of products applicable for the prediction of the risk of GP.

3 ex, 3 tbl, 1 dwg

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RU 2 560 842 C1

Authors

Kamoeva Svetlana Viktorovna

Makarov Oleg Vasil'Evich

Khadzhieva Mar'Jam Borisovna

Ivanova Anastasija Vladimirovna

Chumachenko Anastasija Gennad'Evna

Abilev Serikbaj Karimovich

Sal'Nikova Ljubov' Efimovna

Dates

2015-08-20—Published

2014-04-29—Filed