METHOD OF PREDICTING DEVELOPMENT OF PELVIC AND URODYNAMIC DYSFUNCTIONS IN WOMEN AFTER CHILDBIRTH Russian patent published in 2023 - IPC A61B5/20 A61B5/24 A61B8/12 G01N33/50 

FIELD: medicine; obstetrics; gynecology.

SUBSTANCE: following is determined: carriage of the GG genotype of the ESR1:A-351G gene, parity of births, the pressure exerted by the pelvic floor muscles during contraction on the vaginal perineometer sensor, the size of the tendon center, the thickness of the bulbospongiosus muscle, the difference in the width of the urethra at rest and when straining according to the results of an ultrasound examination of the pelvic floor. The prognostic index W is calculated using the formula

where W is a prognostic index for the probability of developing pelvic and urodynamic dysfunctions in women 6 months after childbirth,

x1 is presence of first birth, 0 is no, 1 is yes;

x2 is difference in the width of the urethra at rest and during straining according to ultrasound examination of the lower urinary tract (mm);

x3 is measurement value of the pressure exerted on the vaginal sensor during contraction of the pelvic floor muscles according to the results of perineometry (mm Hg);

x4 is carriage of the GG genotype in -351 locus of ESR1 A>G gene;

x5 is the size of the tendon center of the perineum according to the results of ultrasound examination of the pelvic floor (mm);

x6 is a value m. bulbospongiosus according to the results of ultrasound examination of the pelvic floor (mm). The probability W varies from 0 to 1, with W > 0.5 a high risk of developing pelvic and urodynamic dysfunctions in women 6 months after childbirth is predicted.

EFFECT: method makes it possible to predict the risk of developing pelvic and urodynamic dysfunctions in women 6 months after childbirth by calculating the prognostic risk and to identify a high-risk group in case of formation of this pathology.

1 cl, 2 ex