FIELD: medicine.
SUBSTANCE: alloxan is introduced into rat's peritoneum in a dose of 15.0 mg/100 g of weight. Then, 6.5 weeks after alloxan has been introduced, and experimental diabetes has been developed, insulin-like growth factor 1 (IGF-1) 1 mcl is introduced into the vitreous body from an intravitreous approach.
EFFECT: method simplifies and reduces the length of formation of persistent primary macular oedema specific for diabetes mellitus, enables analysing the course of the pathological process, forming the new therapeutic regimens.
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Authors
Dates
2013-11-10—Published
2012-07-24—Filed