METHOD FOR TREATING NEPHROANGIOPATHY COMBINED WITH ALLOXAN DIABETES IN EXPERIMENTAL ANIMALS Russian patent published in 2009 - IPC A61K31/197 A61P13/12 G09B23/28 

Abstract RU 2372898 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to endocrinology and nephrology, and concerns treating nephroangiopathy combined with experimental alloxan diabetes. Modelling of diabetes is ensured by single intraperitoneal introduction of 5% aqueous solution of alloxan in a dose 15 mg per kg of an animal's weight. Two weeks later L-carnitine is injected subcutaneously in a dose 25 mg per 100 g of an animal's weight daily once a day during 4 weeks.

EFFECT: method provides effective treatment of nephroangiopathy in specific experimental conditions due to lower lipid peroxidation in cell membranes of kidney vessels and improved renal blood flow.

6 tbl, 1 ex, 10 dwg

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RU 2 372 898 C1

Authors

Dzugkoev Sergej Gavrilovich

Khetagurova Larisa Georgievna

Dzugkoeva Fira Solomonovna

Dates

2009-11-20Published

2008-09-29Filed