8-ANILINOIMIDAZOPYRIDINES AND METHODS FOR USE THEREOF Russian patent published in 2013 - IPC C07D471/04 A61K31/437 A61P35/00 

FIELD: chemistry.

SUBSTANCE: invention relates to imidazopyridines of formula I and to a pharmaceutically acceptable salt thereof, where Z¹ is CR¹; R¹ is H; R^1' is H; Z² is CR²; Z³ is CR³; R² and R³ are H; R⁴ is H; Y is W-C(O)-; W is or ; R⁵ is H; X¹ is selected from R¹¹' and -OR¹¹'; R¹¹ is independently H or C₁-C₆ alkyl, optionally substituted -(CR¹⁹R²⁰)_nCOR¹⁶; X⁴ is ; R⁶ is halogen, carbocyclyl or -(CR¹⁹R²⁰)_n-SR¹⁶, wherein said carbocyclyl is cyclopropyl or cyclobutyl; R^6' is halogen; p equals 1, 2; n equals 0, 1; each R¹⁶ is independently H or C₁-C₆ alkyl; R¹⁹ and R²⁰ are independently selected from H or C₁-C₆ alkyl. The invention also relates to a pharmaceutical composition based on the compound of formula I and a method of inhibiting anomalous cell growth or treating a hyperproliferative disorder, based on use of the compound of formula I.

EFFECT: obtaining novel imidazopyridine derivatives of formula I, which are useful in treating hyperproliferative disorders.

7 cl, 14 ex