FIELD: biotechnologies.
SUBSTANCE: invention refers to conjugate of gossypol with sodium-carboxymethyl cellulose with molecular mass of 780-180000 Da at the ratio of gossypol to sodium-carboxymethyl cellulose of (1-5):(99-95) wt % and content of low-molecular fraction with molecular mass of 780 to 1500 Da of up to 20% and high-molecular fraction with molecular mass of 1500 to 180000 Da of up to 80%, conjugate of gossypol with sodium-carboxymethyl cellulose with molecular mass of 780 to 1500 Da at the ratio of gossypol to sodium-carboxymethyl cellulose of (0.35-1.76):(99.65-98.24) wt %, and conjugate of gossypol with sodium-carboxymethyl cellulose with molecular mass of 1500 to 180000 Da at the ratio of gossypol to sodium-carboxymethyl cellulose of (0.65-3.23):(99.35-96.77) wt %, and their production methods. Besides, the invention refers to antiviral agents on the basis of the above conjugates and pharmaceutical compositions containing conjugates.
EFFECT: improving compound application efficiency.
21 cl, 5 tbl, 3 dwg
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