ASYMMETRIC DERIVATIVES OF DINAPHTHALENE POLYPHENOLS, THEIR PRODUCTION METHOD AND APPLICATION Russian patent published in 2022 - IPC C07C47/57 C07C50/38 C07C69/734 C07C251/24 C07C45/65 C07C45/61 C07C46/02 C07C67/00 C07C249/02 A61K31/11 A61K31/122 A61K31/216 A61P31/12 

Abstract RU 2766222 C2

FIELD: medicine.

SUBSTANCE: present invention relates to asymmetric derivatives of dinaphthalene polyphenols of the general Formula (I) or the general Formula (II) , to their production methods and to their use as antiviral agent effective relatively to influenza A virus. In the formula I, R1 is: C(O)H, CH=N-R8, where R8 is: linear and branched C1-C20 alkyl substituted with phenyl; R2, R3, R3a, R5, R5a, R7, R7a are H; R2a is: H, linear and branched C1-C20 alkyl substituted with COOR8a, where R8a is: H, linear and branched C1-C20 alkyl; R4, R4a, R6 and R6a are independently linear and branched C1-C10 alkyl. In the formula II, R1 is: C(O)H; R2, R3, R2a, R3a are H; R4, R4a, R6 and R6a are independently H, linear or branched C1-C10 alkyl.

EFFECT: obtaining an antiviral agent for the treatment of influenza A virus.

16 cl, 5 dwg, 2 tbl

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RU 2 766 222 C2

Authors

Nesterenko Vladimir Georgievich

Suslov Anatolij Petrovich

Tsyrulnikov Sergej Aleksandrovich

Nenashev Mikhail Nikolaevich

Kiseleva Irina Vladislavovna

Kuznetsov Vitalij Vladimirovich

Dates

2022-02-10Published

2017-12-26Filed