FIELD: chemistry.
SUBSTANCE: invention relates to the novel gossypol derivatives which can be used in pharmacology, having the general formula (I):
where RI=Sach; RII=Sach or H; Sach is an oxidised polysaccharide residue, having a unit of one of the formulae given below:
where n denotes the polymery of a compound containing from 1 oxidised unit per 1000 saccharide units of polysaccharide to completely oxidised polysaccharide, where the polysaccharide is selected from carboxymethyl cellulose or dextran, and the weight-average molecular weight Mw of 1 to 2000 kDa, preferably 3 to 80 kDa. Disclosed are novel gossypol derivatives with antiviral activity and an efficient method for production thereof, which includes reacting an oxidised polysaccharide having units of formulae: 
containing from 1 oxidised unit per 1000 saccharide units of polysaccharide to completely oxidised polysaccharide, with gossypol at pH 3.5-14 and molar ratio of gossypol:oxidised polysaccharide unit of 10:1 to 1:100.
EFFECT: improved properties of the composition.
10 cl, 5 tbl, 4 dwg
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