FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine. A composition for treating an ear disease is introduced into the tympanic cavity, contains a polyoxyethylene-polyoxypropylene copolymer, an active substance specified in an immunomodulator, a vasopressin antagonist, an ion channel antagonist, a neurokinin receptor antagonist, a serotonin reuptake inhibitor, an NMDA-receptor antagonist, a prostaglandin analogue, a preparation having an effect on the central nervous system, a GABA receptor modulator, a cytotoxic agent, an antioxidant, a glutamate receptor modulator or a calcineurin inhibitor.
EFFECT: invention provides the prolonged release of the active substance into the internal ear for a period of time of at least 7 days.
14 cl, 3 dwg, 114 ex
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Authors
Dates
2013-11-27—Published
2009-04-21—Filed